SCHEMBL3373773

SCHEMBL3373773

C(=C/c1ccc(-c2cccc3c2[nH]c2ccccc23)cc1)\c1ccc(-c2cccc3c2[nH]c2ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 7/20 0.50
KDM4E B2RXH2 5/20 0.50
MAPT P10636 5/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 2/20 0.50
ATM Q13315 2/20 0.50
MAPK1 P28482 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 4/20 0.49
GAA P10253 3/20 0.49
POLB P06746 2/20 0.49
S1PR4 O95977 1/20 0.49
LMNA P02545 1/20 0.49
S1PR1 P21453 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
KIF11 P52732 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2568513 1.00 GLA (0.50) GLAKDM4EMAPTMEN1KMT2A
SCHEMBL29882533 1.00 GLA (0.50) GLAKDM4EMAPTMEN1KMT2A
SCHEMBL29253380 0.91 KIF11 (0.46) GLAKDM4EMAPTMEN1KMT2A
SCHEMBL208888 0.89 KIF11 (0.57) ALDH1A1KIF11PARP14BCHECDK4
SCHEMBL29407801 0.89 KIF11 (0.57) ALDH1A1KIF11PARP14BCHECDK4
SCHEMBL30641449 0.89 KIF11 (0.57) ALDH1A1KIF11PARP14BCHECDK4
SCHEMBL38828 0.89 KIF11 (0.57) ALDH1A1KIF11PARP14BCHECDK4
SCHEMBL1326376 0.89 KIF11 (0.57) ALDH1A1KIF11PARP14BCHECDK4
SCHEMBL1326378 0.88 KIF11 (0.55) ALDH1A1KIF11PARP14BCHECDK4
SCHEMBL442417 0.87 KIF11 (0.53) MAPTMEN1KMT2AKIF11PARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2236488-A1 Materials, methods and uses for photochemical generation of acids and/or radical species The Arizona Board of Regents on behalf of the University of Arizona (US) 2010-10-06 EP disclosed
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
EP-1390664-A4 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES UNIV ARIZONA (US) 2008-01-02 EP disclosed
US-20050173683-A1 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZ BD OF REGENTS ON BEHALF OF THE UNIV OF AZ (US) 2005-08-11 US disclosed
EP-1390664-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES The Arizona Board of Regents (US) 2004-02-25 EP disclosed
WO-2002079691-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2002-10-10 WO disclosed