SCHEMBL3374288

SCHEMBL3374288

O=C1OC(=O)O[C@@H]2CCCC[C@@H]2O1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
PPM1B O75688 1/20 0.33
LMNA P02545 1/20 0.33
PPP1CC P36873 1/20 0.33
TFPI2 P48307 1/20 0.33
RAB9A P51151 1/20 0.33
PPP5C P53041 1/20 0.33
PPP1CA P62136 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
TSHR P16473 1/20 0.32
PRSS1 P07477 2/20 0.31
CTRC Q99895 2/20 0.31
F2 P00734 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3369402 1.00 KDM4E (0.33) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL300128 1.00 KDM4E (0.33) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL8994775 0.97 KDM4E (0.32) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL7595334 0.94 PRSS1 (0.34) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL3919467 0.88 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL5177038 0.88 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL13783610 0.88 PRSS1 (0.32) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2351624 0.88 PRSS1 (0.32) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL16221630 0.88 PRSS1 (0.32) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL14219148 0.88 PRSS1 (0.32) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091992-B1 RESIN SYSTEM ABB SCHWEIZ AG (CH) 2003-12-03 EP claimed
EP-1354916-A1 Self-hardening epoxy resin for the manufacture of electric insulators ABB RESEARCH LTD. (CH) 2003-10-22 EP claimed
EP-1091992-A1 RESIN SYSTEM ABB Corporate Research Ltd. (CH) 2001-04-18 EP claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
WO-1999067315-A1 RESIN SYSTEM ABB CORPORATE RESEARCH LTD. (CH) 1999-12-29 WO claimed
EP-4127021-A1 METHOD FOR PRODUCING AN ETHER ESTEROL Covestro Deutschland AG (DE) 2023-02-08 EP disclosed
WO-2021191069-A1 METHOD FOR PRODUCING AN ETHER ESTEROL COVESTRO DEUTSCHLAND AG (DE) 2021-09-30 WO disclosed
EP-1730220-B1 METHOD FOR PRODUCING A CROSS-LINKED PVC FOAM BODY 3A TECHNOLOGY & MAN AG (CH) 2010-10-20 EP disclosed
US-20070200266-A1 Method For Producing A Cross-Linked Pvc Foam Body ALCAN TECHNOLOGY & MANAGEMENT LTD. (CH) 2007-08-30 US disclosed
EP-1582545-A1 Process for the preparation of a crosslinked PVC foam part. Alcan Technology & Management Ltd. (CH) 2005-10-05 EP disclosed
EP-1568733-A1 Porous inorganic filler particles having an organopolysiloxane coating for use in curable casting compositions ABB RESEARCH LTD. (CH) 2005-08-31 EP disclosed
EP-1075500-A1 WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-02-14 EP disclosed
WO-1999067315-A1 RESIN SYSTEM ABB CORPORATE RESEARCH LTD. (CH) 1999-12-29 WO disclosed
WO-1999058612-A1 WATER-SOLUBLE MONOAZO COMPOUNDS, METHOD FOR PRODUCING SAME AND THEIR USE AS DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-11-18 WO disclosed
EP-0392317-B1 Benzimidazoles, drugs containing these compounds and process for their preparation THOMAE GMBH DR K (DE) 1996-01-03 EP disclosed
EP-0002725-B1 FILM FORMING COMPOSITION FOR COATING THE PINS OF A MODULE International Business Machines Corporation (US) 1984-05-30 EP disclosed
EP-0009465-A1 N-(1-(4-amino-2-quinazolinyl)-3 or 4-piperidyl lactames, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1980-04-02 EP disclosed
EP-0002725-A1 Film forming composition for coating the pins of a module International Business Machines Corporation (US) 1979-07-11 EP disclosed