Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PPP5C | P53041 | 1/20 | 0.32 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369402 | 0.97 | KDM4E (0.33) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL3374288 | 0.97 | KDM4E (0.33) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL300128 | 0.97 | KDM4E (0.33) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL7595334 | 0.92 | PRSS1 (0.34) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL8083570 | 0.89 | KMT2A (0.33) | KMT2AHSD11B1DAO | |
| SCHEMBL11351258 | 0.89 | KMT2A (0.33) | KMT2AHSD11B1DAO | |
| SCHEMBL16221696 | 0.89 | KMT2A (0.33) | KMT2AHSD11B1DAO | |
| SCHEMBL3920971 | 0.87 | ALDH1A1 (0.30) | — | |
| SCHEMBL5177038 | 0.86 | KDM4E (0.42) | KDM4EGMNNPPM1BLMNAPPP1CC | |
| SCHEMBL3919467 | 0.86 | KDM4E (0.42) | KDM4EGMNNPPM1BLMNAPPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614457-B1 | LEUKOTRIENE-B 4? DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | SCHERING AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0614457-A1 | LEUKOTRIENE-B 4? DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS. | SCHERING AG (DE) | 1994-09-14 | — | — | EP | disclosed |
| WO-1993011105-A1 | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-10 | — | — | WO | disclosed |