SCHEMBL3374641

SCHEMBL3374641

CO[Si](C)(OC)C(C)C(=O)S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28447376 0.79 TP53 (0.38)
SCHEMBL3376057 0.78
SCHEMBL3376145 0.77
SCHEMBL21177882 0.75 SMN1; SMN2 (0.41)
SCHEMBL3373098 0.75
SCHEMBL9835602 0.73
SCHEMBL22614810 0.71 TSHR (0.39)
SCHEMBL21177764 0.70 ALDH1A1 (0.39)
SCHEMBL3374306 0.68
SCHEMBL21177635 0.67 HCAR2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978768-B1 CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE MOMENTIVE PERFORMANCE MAT INC (US) 2017-11-29 EP claimed
EP-1341843-B2 MINERAL-FILLED ELASTOMER COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2016-03-23 EP claimed
EP-1560836-B1 PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-30 EP claimed
EP-1669401-B1 Tire with tread containing combination of specialized elastomer and coupling agent GOODYEAR TIRE & RUBBER (US) 2013-07-31 EP claimed
EP-1491545-B1 Method of preparing a composite of hydrophobated amorphous silica employing blocked mercaptoalkoxysilanes GOODYEAR TIRE & RUBBER (US) 2009-01-14 EP claimed
EP-0958298-B2 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS MOMENTIVE PERFORMANCE MAT INC (US) 2008-10-22 EP claimed
EP-1341843-B1 MINERAL-FILLED ELASTOMER COMPOSITIONS GEN ELECTRIC (US) 2007-01-17 EP claimed
EP-0958298-B1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS CROMPTON CORP (US) 2003-05-07 EP claimed
US-20260132274-A1 TIRE COMPONENT FROM RUBBER COMPOSITION INCLUDING GUAYULE RUBBER AND EUTECTIC COMPOSITION AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2026-05-14 US disclosed
US-20260071068-A1 RESIN-EXTENDED RUBBER AND PROCESS FOR PREPARING BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2026-03-12 US disclosed
EP-4055098-B1 TIRE HAVING TREAD OF SPECIFIED RUBBER COMPOSITION AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2025-12-24 EP disclosed
US-12466214-B2 Tire tread rubber composition BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-11-11 US disclosed
EP-3255113-B1 ADHESIVE AND/OR SEALANT COMPOSITION WITH HIGH INITIAL TACK SOUDAL (BE) 2025-11-05 EP disclosed
US-20250333585-A1 Tire Tread Rubber Composition BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-10-30 US disclosed
US-7256231-B2 Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes BRIDGESTONE CORPORATION (JP) 2007-08-14 US disclosed
US-20060106143-A1 Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes BRIDGESTONE CORPORATION 2006-05-18 US disclosed
EP-1609516-A1 Process and device for extracting substances from silan-modified fillers Degussa AG (DE) 2005-12-28 EP disclosed
EP-1256604-B1 Biopolymers, biooligomers, oxidic or silicate Filler modified by silanes, method for its production and use DEGUSSA (DE) 2005-08-31 EP disclosed
EP-1357156-A2 Silane modified oxidic or silicate filler, method for its manufacture and its use Degussa AG (DE) 2003-10-29 EP disclosed
EP-1256604-A2 Biopolymers, biooligomers, oxidic or silicate Filler modified by silanes, method for its production and use Degussa AG (DE) 2002-11-13 EP disclosed