Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27818387 | 1.00 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL28945200 | 0.80 | POLB (0.39) | — | |
| SCHEMBL27812348 | 0.80 | POLB (0.39) | — | |
| SCHEMBL1712274 | 0.77 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL2287472 | 0.75 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL15791814 | 0.75 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL15791725 | 0.75 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL2288859 | 0.74 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL2288866 | 0.74 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL15791714 | 0.74 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164925-A | Tricyclic oxazolidinone antibiotic compounds | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
| WO-2010041194-A1 | TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-15 | — | — | WO | disclosed |