Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812348 | 1.00 | POLB (0.39) | POLBMEN1KMT2AAPAF1HTT | |
| SCHEMBL27820798 | 0.89 | POLB (0.38) | POLBMEN1KMT2AAPAF1HTT | |
| SCHEMBL27832796 | 0.82 | ALDH1A1 (0.44) | KMT2AALDH1A1TRPV1GAA | |
| SCHEMBL592252 | 0.81 | HTT (0.41) | POLBMEN1KMT2AAPAF1HTT | |
| SCHEMBL592251 | 0.81 | HTT (0.41) | POLBMEN1KMT2AAPAF1HTT | |
| SCHEMBL3375299 | 0.80 | KCNH2 (0.34) | — | |
| SCHEMBL27818387 | 0.80 | KCNH2 (0.34) | — | |
| SCHEMBL3333028 | 0.80 | HTT (0.40) | POLBHTTALDH1A1LMNATRPV1 | |
| SCHEMBL3333023 | 0.80 | HTT (0.40) | POLBHTTALDH1A1LMNATRPV1 | |
| SCHEMBL592187 | 0.77 | MAOA (0.51) | POLBHTTALDH1A1LMNATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164919-A | Oxazolidinyl antibiotics | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
| CN-102105467-A | Tricyclic alkylaminomethyloxazolidinone derivatives | ACTELION PHARMACEUTICALS LTD | 2011-06-22 | — | — | CN | disclosed |