Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372729 | 0.87 | PPARD (0.34) | PPARDALDH1A1HSP90AA1 | |
| SCHEMBL3375669 | 0.84 | PPARD (0.44) | PPARDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3026125 | 0.81 | PPARD (0.71) | PPARD | |
| SCHEMBL3021922 | 0.79 | PPARD (0.49) | PPARDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3021925 | 0.79 | PPARD (0.49) | PPARDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3372723 | 0.75 | PPARD (0.36) | PPARDALDH1A1 | |
| SCHEMBL3375667 | 0.72 | PPARD (0.46) | PPARDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3266067 | 0.71 | PPARD (0.55) | PPARDALDH1A1 | |
| SCHEMBL3021862 | 0.70 | PPARD (0.56) | PPARD | |
| SCHEMBL3033687 | 0.70 | PPARD (0.56) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745002-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-11-03 | — | — | EP | claimed |
| EP-1745002-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-11-03 | — | — | EP | disclosed |