Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375667 | 0.88 | PPARD (0.46) | PPARDPPARAALDH1A1VCPPYCR1 | |
| SCHEMBL3375341 | 0.84 | PPARD (0.44) | PPARDALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3026854 | 0.83 | PPARD (0.69) | PPARDPPARA | |
| SCHEMBL3026852 | 0.83 | PPARD (0.69) | PPARDPPARA | |
| SCHEMBL3373878 | 0.82 | PPARD (0.48) | PPARDPPARAALDH1A1CYP3A4MEN1 | |
| SCHEMBL3021753 | 0.80 | PPARD (0.48) | PPARDPPARAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3021757 | 0.80 | PPARD (0.48) | PPARDPPARAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3372729 | 0.77 | PPARD (0.34) | PPARDPPARAALDH1A1MEN1NPC1 | |
| SCHEMBL3371272 | 0.76 | PPARD (0.33) | PPARDPPARACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3027968 | 0.72 | PYCR1 (0.39) | PPARDALDH1A1VCPPYCR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745002-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-11-03 | — | — | EP | claimed |