SCHEMBL337582

SCHEMBL337582

COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 5/20 1.00
HIF1A Q16665 3/20 1.00
VDR P11473 3/20 1.00
CYP2C9 P11712 2/20 1.00
EPHA2 P29317 5/20 0.79
CASP7 P55210 3/20 0.79
MAPK1 P28482 3/20 0.79
MAPT P10636 3/20 0.79
USP2 O75604 3/20 0.79
TP53 P04637 2/20 0.79
HSD17B10 Q99714 2/20 0.79
BLM P54132 2/20 0.79
TDP1 Q9NUW8 2/20 0.79
LMNA P02545 2/20 0.79
CYP3A4 P08684 2/20 0.79
MDM4 O15151 1/20 0.79
HSPD1 P10809 1/20 0.79
TSHR P16473 1/20 0.79
PTPN2 P17706 1/20 0.79
PTPN1 P18031 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14269208 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL14771006 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL12205283 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL12917358 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL23776966 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL21283583 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL23285666 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL14359988 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL22079995 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2
SCHEMBL12704721 1.00 GPBAR1 (1.00) GPBAR1HIF1AVDRCYP2C9EPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081890-A Preparation method of 7-ketolithocholic acid 上海格苓凯生物科技有限公司 2025-06-03 CN claimed
CN-110023324-A For treating the squalamine ester derivant of infection 维克公司 2019-07-16 CN claimed
US-9939747-B2 Developing agent and method for producing the same TOSHIBA TEC KABUSHIKI KAISHA (JP) 2018-04-10 US claimed
US-20170038698-A1 DEVELOPING AGENT AND METHOD FOR PRODUCING THE SAME TOSHIBA TEC KABUSHIKI KAISHA (JP) 2017-02-09 US claimed
CN-1326461-A Meiosis regulating compounds NOVO NORDISK AS (DK) 2001-12-12 CN claimed
US-20250319191-A1 PHARMACEUTICAL COMPOSITION COMPRISING HYALURONIC ACID COMPLEX FOR PREVENTION OR TREATMENT OF SKIN DISEASE UNIV AJOU IND ACADEMIC COOP FOUND (KR) 2025-10-16 US disclosed
CN-120081890-A Preparation method of 7-ketolithocholic acid 上海格苓凯生物科技有限公司 2025-06-03 CN disclosed
EP-4371578-A1 PHARMACEUTICAL COMPOSITION COMPRISING HYALURONIC ACID COMPLEX FOR PREVENTION OR TREATMENT OF SKIN DISEASE Ajou University Industry-Academic Cooperation Foundation (KR) 2024-05-22 EP disclosed
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
US-11629166-B2 Compound for treating clostridium difficile ASTON UNIVERSITY (GB) 2023-04-18 US disclosed
CN-115819491-A Synthesis method of 7-ketolithocholic acid and ursodeoxycholic acid 江苏佳尔科药业集团股份有限公司 2023-03-21 CN disclosed
US-11555099-B2 Method for producing colorable material TOSHIBA TEC KABUSHIKI KAISHA (JP) 2023-01-17 US disclosed
US-5695738-A Steroidal C-glycosides GLYCOMED INCORPORATED (US) 1997-12-09 US disclosed
US-5266566-A Method of treating fungal infections using sterodial ester compounds BRITISH TECHNOLOGY GROUP LIMITED 1993-11-30 US disclosed
US-5158855-A α-diazoacetoacetates and photosensitive resin compositions containing the same HITACHI, LTD. (JP) 1992-10-27 US disclosed
EP-0470995-A1 USE OF STEROIDAL COMPOUNDS AS ANTI-FUNGAL AGENTS. NAT RES DEV (GB) 1992-02-19 EP disclosed
WO-1990013298-A1 USE OF STEROIDAL COMPOUNDS AS ANTI-FUNGAL AGENTS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1990-11-15 WO disclosed
US-4705847-A Polycycloalkylidene-polycycloalkanes, epidioxy derivatives thereof and method of preparation AKZO N.V. (NL) 1987-11-10 US disclosed
US-4354972-A Synthesis of steroids KAISER EMIL T 1982-10-19 US disclosed
US-4284577-A Novel vitamin D3 derivative and process for preparing the same Yamada, Sachiko (JP) 1981-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11629166-B2 Compound for treating clostridium difficile DSTN, DAD1, DDOST GPBAR1 77/4885HIF1A 3157/4885VDR 1537/4885
US-20250319191-A1 PHARMACEUTICAL COMPOSITION COMPRISING HYALURONIC ACID COMPLEX FOR PREVENTION OR TREATMENT OF SKIN DISEASE TLR4, CD44, TLR1 GPBAR1 1780/4885HIF1A 140/4885VDR 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.