Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17747764 | 1.00 | GABRR1 (0.30) | GABRR1 | |
| SCHEMBL4600592 | 0.79 | GABRR1 (0.39) | GABRR1 | |
| SCHEMBL17747646 | 0.79 | — | — | |
| SCHEMBL2541422 | 0.75 | DPP4 (0.30) | — | |
| SCHEMBL18340860 | 0.75 | DPP4 (0.30) | — | |
| SCHEMBL3183946 | 0.71 | GABRR1 (0.33) | GABRR1 | |
| SCHEMBL3197102 | 0.71 | GABRR1 (0.33) | GABRR1 | |
| SCHEMBL15193898 | 0.71 | GABRR1 (0.33) | GABRR1 | |
| SCHEMBL15194169 | 0.71 | GABRR1 (0.33) | GABRR1 | |
| SCHEMBL321958 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863477-B1 | 3,4-SUBSTITUTED PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF HYPERTENSION | NOVARTIS AG (CH) | 2010-11-03 | — | — | EP | disclosed |