Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867305 | 0.89 | THRA (0.51) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL9504751 | 0.89 | THRA (0.51) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL9504746 | 0.89 | THRA (0.51) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL9560107 | 0.85 | THRA (0.50) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL9560108 | 0.85 | THRA (0.50) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL7867315 | 0.85 | THRA (0.50) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL24611344 | 0.84 | THRA (0.48) | THRATHRBLIPGPTGER4PTGER3 | |
| SCHEMBL9559967 | 0.83 | THRA (0.48) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL9559968 | 0.83 | THRA (0.48) | THRATHRBPPARALIPGPTGER4 | |
| SCHEMBL489896 | 0.82 | PTGER3 (0.54) | THRATHRBPPARALIPGPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150458-A1 | SILICONE-MODIFIED WAX, COMPOSITION AND COSMETIC PREPARATION CONTAINING THE SAME, AND PRODUCTION METHOD OF SILICONE-MODIFIED WAX | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-06-13 | — | — | US | disclosed |
| EP-2602279-A1 | Silicone-modified wax, composition and cosmetic preparation containing the same, and production method of silicone-modified wax | Shin-Etsu Chemical Co., Ltd. (JP) | 2013-06-12 | — | — | EP | disclosed |
| EP-1632213-B1 | COSMETIC PREPARATION | SHINETSU CHEMICAL CO (JP) | 2010-11-03 | — | — | EP | disclosed |
| US-7413744-B2 | Cosmetic preparation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-08-19 | — | — | US | disclosed |
| US-20060128882-A1 | Cosmetic preparation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1632213-A1 | COSMETIC PREPARATION | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150458-A1 | SILICONE-MODIFIED WAX, COMPOSITION AND COSMETIC PREPARATION CONTAINING THE SAME, AND PRODUCTION METHOD OF SILICONE-MODIFIED WAX | FASN, FADS2, STS | THRA 63/4885THRB 310/4885PPARA 558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.