⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611831 | 0.77 | — | — | |
| SCHEMBL22865268 | 0.74 | — | — | |
| SCHEMBL13567228 | 0.72 | — | — | |
| SCHEMBL25916784 | 0.72 | — | — | |
| SCHEMBL14223706 | 0.72 | — | — | |
| SCHEMBL7724511 | 0.72 | — | — | |
| SCHEMBL7535294 | 0.72 | — | — | |
| SCHEMBL4591310 | 0.69 | — | — | |
| SCHEMBL21721766 | 0.69 | CNR1 (0.34) | — | |
| SCHEMBL22081185 | 0.69 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620902-B | Preparation of 2-chloro-5-chloro-methylthiazole in tower reactor | 邯郸市瑞田农药有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-113620902-A | Preparation of 2-chloro-5-chloro-methylthiazole by tower reactor | 邯郸市瑞田农药有限公司 | 2021-11-09 | — | — | CN | claimed |
| EP-1309574-B1 | METHOD FOR PURIFYING 2-CHLORO-5-CHLOROMETHYL THIAZOLE | BAYER CROPSCIENCE AG (DE) | 2005-06-08 | — | — | EP | claimed |
| EP-0260560-B1 | PROCESS FOR THE PREPARATION OF 2-CHLOR-5-CHLORMETHYL THIAZOLE | BAYER AG (DE) | 1990-05-16 | — | — | EP | claimed |
| CN-113620902-B | Preparation of 2-chloro-5-chloro-methylthiazole in tower reactor | 邯郸市瑞田农药有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-113620902-B | Preparation of 2-chloro-5-chloro-methylthiazole in tower reactor | 邯郸市瑞田农药有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-113620902-B | Preparation of 2-chloro-5-chloro-methylthiazole in tower reactor | 邯郸市瑞田农药有限公司 | 2023-08-18 | — | — | CN | disclosed |
| WO-2023110138-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023092781-A1 | PREPARATION METHOD FOR REVERSE OSMOSIS MEMBRANE, AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY | 沃顿科技股份有限公司 | 2023-06-01 | — | — | WO | disclosed |
| CN-116159449-A | Method for preparing reverse osmosis membrane and reverse osmosis membrane prepared by same | 沃顿科技股份有限公司 | 2023-05-26 | — | — | CN | disclosed |
| WO-2023275337-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023275333-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| WO-1998045279-A1 | PREPARATION OF THIAZOLES USING 1,3-DIHALOPROPENES | REILLY INDUSTRIES, INC. (US) | 1998-10-15 | — | — | WO | disclosed |
| US-5811555-A | Method for substitution of an amino group of a primary amine by a chlorine atom and a synthetic method by application thereof | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0348737-B1 | HETEROARYLOXY-ACETIC ACID N-ISOPROPYL ANILIDES | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-5090991-A | HERBICIDAL N-ISOPROPYLHETEROARYLOXYACETANILIDES | BAYER AKATIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4968342-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0348737-A1 | Heteroaryloxy-acetic acid N-isopropyl anilides | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |
| EP-0296453-A2 | Nitrosubstituted heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0235725-A2 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1987-09-09 | — | — | EP | disclosed |