⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154036 | 0.72 | — | — | |
| SCHEMBL3375995 | 0.72 | — | — | |
| SCHEMBL13700990 | 0.72 | — | — | |
| SCHEMBL15751859 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28926886 | 0.70 | — | — | |
| SCHEMBL4104913 | 0.68 | — | — | |
| SCHEMBL7724511 | 0.68 | — | — | |
| SCHEMBL25916784 | 0.68 | — | — | |
| SCHEMBL2514326 | 0.67 | ALDH1A1 (1.00) | — | |
| Hydrochloric Acid SCHEMBL8761196 | 0.66 | ALDH1A1 (0.96) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202979-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2002-05-08 | — | — | EP | claimed |
| WO-2001010852-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-02-15 | — | — | WO | claimed |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |