SCHEMBL3376137

SCHEMBL3376137

C#CCNCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1159492 0.74
SCHEMBL38356 0.73
SCHEMBL3921048 0.73
SCHEMBL24425891 0.72
SCHEMBL11670427 0.72
SCHEMBL7124693 0.72
SCHEMBL24627771 0.70
Hydrochloric Acid SCHEMBL11469944 0.70
SCHEMBL14916620 0.69 L3MBTL1 (0.41)
SCHEMBL14916621 0.69 L3MBTL1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2044083-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. (US) 2009-04-08 EP claimed
US-20080051384-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. 2008-02-28 US claimed
WO-2008008907-A2 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. (US) 2008-01-17 WO claimed
WO-2008008912-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. (US) 2008-01-17 WO claimed
US-20060211698-A1 Bicyclic heteroaryl derivatives for treating viruses GENELABS, INC. 2006-09-21 US claimed
US-20180093992-A1 PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS MERCK SHARP & DOHME LLC 2018-04-05 US disclosed
US-9862725-B2 Process for preparing chiral dipeptidyl peptidase-IV inhibitors MERCK SHARP & DOHME CORP. (US) 2018-01-09 US disclosed
US-20170158701-A1 PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS MERCK SHARP & DOHME LLC 2017-06-08 US disclosed
US-20170158701-A1 PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS MERCK SHARP & DOHME LLC 2017-06-08 US disclosed
WO-2016014324-A1 PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS MERCK SHARP & DOHME CORP. (US) 2016-01-28 WO disclosed
EP-2190289-A2 ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS Intervet International B.V. (NL) 2010-06-02 EP disclosed
EP-2049536-A2 POLYCYCLIC VIRAL INHIBITORS GENELABS TECHNOLOGIES, INC. (US) 2009-04-22 EP disclosed
US-4045446-A 1-Benzothiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-08-30 US disclosed
US-4043795-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-08-23 US disclosed
US-4036848-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-07-19 US disclosed
US-4033753-A HERICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-07-05 US disclosed
US-4029491-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-06-14 US disclosed
US-4028375-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-06-07 US disclosed
US-4018787-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-04-19 US disclosed
US-4008068-A HERBICIDE VELSICOL CHEMICAL CORPORATION (US) 1977-02-15 US disclosed