Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413387 | 1.00 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL27965166 | 0.86 | PDPK1 (0.49) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL24105930 | 0.81 | PDPK1 (0.56) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL14521490 | 0.81 | PDPK1 (0.56) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL19114860 | 0.81 | PDPK1 (0.56) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL30047267 | 0.80 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL3375618 | 0.80 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL3375614 | 0.80 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL30468602 | 0.80 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DPDPK1 | |
| SCHEMBL30407788 | 0.79 | ALDH1A1 (0.55) | PDE4APDE4BPDE4CPDE4DPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049379-A1 | A PROCESS FOR THE PREPARATION OF (R)-I -AMINOINDANES | CHEMO IBÉRICA, S.A. (ES) | 2010-05-06 | — | — | WO | disclosed |
| EP-2181980-A1 | A process for the preparation of (R)-1-aminoindanes | Chemo Ibérica, S.A. (ES) | 2010-05-05 | — | — | EP | disclosed |