Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373848 | 0.87 | — | — | |
| SCHEMBL3372484 | 0.83 | TSHR (0.31) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL180545 | 0.75 | — | — | |
| SCHEMBL18854183 | 0.71 | TSHR (0.35) | TSHRCA1CA2 | |
| SCHEMBL21480767 | 0.71 | TSHR (0.35) | TSHRCA1CA2 | |
| SCHEMBL20408652 | 0.71 | TSHR (0.31) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3377643 | 0.70 | — | — | |
| SCHEMBL20408651 | 0.69 | ADH1B (0.31) | TSHR | |
| SCHEMBL3978227 | 0.69 | TSHR (0.43) | TSHR | |
| SCHEMBL21895942 | 0.68 | ADH1B (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756125-B1 | 1,1,3,3,3-PENTAAMINO-1-OXO/THIO-1LAMBDA5,3LAMBDA5-DIPHOSPHAZ-2-ENES, METHOD FOR PRODUCING THEM AND THEIR USE AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC HYDROLYSIS OF UREA | PIESTERITZ STICKSTOFF (DE) | 2010-11-10 | — | — | EP | disclosed |