Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374575 | 0.83 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3374578 | 0.83 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3374273 | 0.83 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3374571 | 0.83 | KCNH2 (0.43) | KCNH2SLC2A1 | |
| SCHEMBL3375784 | 0.81 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL3373002 | 0.81 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL3373006 | 0.81 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL3375788 | 0.81 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL4792306 | 0.77 | SLC2A1 (0.37) | KCNH2SLC2A1 | |
| SCHEMBL3378451 | 0.74 | KCNH2 (0.40) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987040-B1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-11-10 | — | — | EP | claimed |