Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776249 | 0.81 | KDM1A (0.55) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL31752901 | 0.79 | GPR119 (0.50) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL13717948 | 0.78 | GPR119 (0.58) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL31464611 | 0.78 | GPR119 (0.59) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL12801187 | 0.78 | USP30 (0.49) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL532111 | 0.78 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL14862081 | 0.78 | USP30 (0.51) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL19284642 | 0.78 | PDE4B (0.53) | PDE4BPDE4DPDE4APDE4CKDM1A | |
| SCHEMBL830217 | 0.78 | USP30 (0.45) | KDM1AGPR119USP30KDM4EPKM | |
| SCHEMBL2547209 | 0.77 | GPR119 (0.56) | KDM1AGPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |