Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.75 |
| ▸ | HTR2C | P28335 | 7/20 | 0.64 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376956 | 1.00 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL3376958 | 1.00 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL7055786 | 0.91 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL7055939 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL9671722 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL9671286 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL8437093 | 0.86 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL10566437 | 0.85 | MTNR1A (0.77) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL7055969 | 0.84 | MTNR1A (0.79) | MTNR1AMTNR1BHTR2CHTR2BKDM4E | |
| SCHEMBL10565333 | 0.84 | MTNR1A (0.75) | MTNR1AMTNR1BHTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061074-A1 | INDOLE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2010-06-03 | — | — | WO | disclosed |