Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL3422712 | 0.95 | CD44 (0.46) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL296442 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL8579175 | 0.90 | CD44 (0.46) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL28991313 | 0.76 | ALDH1A1 (0.46) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL29541273 | 0.75 | — | — | |
| SCHEMBL7807 | 0.75 | — | — | |
| Hydrogen Sulfide SCHEMBL28097433 | 0.74 | — | — | |
| SCHEMBL15900790 | 0.73 | — | — | |
| SCHEMBL8646430 | 0.73 | — | — | |
| SCHEMBL5685497 | 0.73 | CYP3A4 (0.53) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012175702-A1 | RIMFAMPICIN ANALOGUE USEFUL FOR INFECTION IMAGING | GE HEALTHCARE LIMITED (GB) | 2012-12-27 | — | — | WO | disclosed |
| EP-1590007-B1 | IMPROVED RADIOMETAL COMPLEX COMPOSITIONS | GE HEALTHCARE LTD (GB) | 2010-11-10 | — | — | EP | disclosed |
| US-20070020177-A1 | Radiometal complex compositions | MCGILL DAVID | 2007-01-25 | — | — | US | disclosed |
| EP-1590007-A1 | IMPROVED RADIOMETAL COMPLEX COMPOSITIONS | GE Healthcare Limited (GB) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069285-A1 | IMPROVED RADIOMETAL COMPLEX COMPOSITIONS | GE HEALTHCARE LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |
| EP-1444990-A1 | Improved Radiometal Complex Compositions | Amersham plc (GB) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020177-A1 | Radiometal complex compositions | RCN1, ERCC5, RAD50 | CYP3A4 4138/4885ALOX15 3399/4885CASP1 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.