Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442151 | 0.96 | HRH3 (0.52) | HRH3GPBAR1BCHEKDM4EMEN1 | |
| SCHEMBL3442149 | 0.96 | HRH3 (0.52) | HRH3GPBAR1BCHEKDM4EMEN1 | |
| SCHEMBL3377707 | 0.86 | HRH3 (0.55) | HRH3BCHEHRH1CCR3KCNH2 | |
| SCHEMBL3380259 | 0.84 | HRH3 (0.45) | HRH3GPBAR1BCHEKDM4EGAA | |
| Hydrochloric Acid SCHEMBL3375938 | 0.84 | HRH3 (0.48) | HRH3GPBAR1KDM4ETDP1MEN1 | |
| Hydrochloric Acid SCHEMBL3375941 | 0.84 | HRH3 (0.48) | HRH3GPBAR1KDM4ETDP1MEN1 | |
| SCHEMBL3378152 | 0.84 | HRH3 (0.43) | HRH3GPBAR1BCHEKDM4EMEN1 | |
| SCHEMBL3442655 | 0.83 | HRH3 (0.46) | HRH3GPBAR1KDM4EGAATDP1 | |
| SCHEMBL3442653 | 0.83 | HRH3 (0.46) | HRH3GPBAR1KDM4EGAATDP1 | |
| Cyclohexane SCHEMBL3380419 | 0.80 | HRH3 (0.57) | HRH3KDM4ETDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |