Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377688 | 0.94 | SLC2A1 (0.36) | SLC2A1KCNH2 | |
| SCHEMBL3377820 | 0.94 | SLC2A1 (0.36) | SLC2A1KCNH2 | |
| SCHEMBL3377827 | 0.94 | SLC2A1 (0.36) | SLC2A1KCNH2 | |
| SCHEMBL3374581 | 0.94 | PTGS2 (0.38) | SLC2A1DRD2DRD3PTGS2KCNH2 | |
| SCHEMBL3376061 | 0.94 | PTGS2 (0.38) | SLC2A1DRD2DRD3PTGS2KCNH2 | |
| SCHEMBL3376066 | 0.94 | PTGS2 (0.38) | SLC2A1DRD2DRD3PTGS2KCNH2 | |
| SCHEMBL3376060 | 0.94 | PTGS2 (0.38) | SLC2A1DRD2DRD3PTGS2KCNH2 | |
| SCHEMBL3377824 | 0.94 | SLC2A1 (0.36) | SLC2A1KCNH2 | |
| SCHEMBL3378412 | 0.78 | KCNH2 (0.51) | SLC2A1KCNH2 | |
| SCHEMBL3378415 | 0.78 | KCNH2 (0.51) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987040-B1 | ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-11-10 | — | — | EP | claimed |