Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.63 |
| ▸ | CA9 | Q16790 | 5/20 | 0.63 |
| ▸ | STS | P08842 | 8/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379139 | 1.00 | CA2 (0.63) | CA2CA9STSCYP3A4CYP1A2 | |
| SCHEMBL3381694 | 0.90 | STS (0.58) | CA2CA9STSCYP3A4TP53 | |
| SCHEMBL3381697 | 0.90 | STS (0.58) | CA2CA9STSCYP3A4TP53 | |
| SCHEMBL5265236 | 0.90 | STS (0.70) | CA2CA9STSCYP3A4CYP1A2 | |
| SCHEMBL6639220 | 0.90 | STS (0.70) | CA2CA9STSCYP3A4CYP1A2 | |
| SCHEMBL3378635 | 0.90 | CA2 (0.58) | CA2CA9STSCYP3A4CYP1A2 | |
| SCHEMBL3378639 | 0.90 | CA2 (0.58) | CA2CA9STSCYP3A4CYP1A2 | |
| SCHEMBL5265240 | 0.90 | STS (0.70) | CA2CA9STSCYP3A4CYP1A2 | |
| SCHEMBL5265994 | 0.90 | STS (0.70) | CA2CA9STSCYP3A4CYP1A2 | |
| SCHEMBL5265990 | 0.90 | STS (0.70) | CA2CA9STSCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599493-B1 | 2-SUBSTITUTED ESTRA-1,3,5(10)-TRIENE-3-YL SULFAMATE WITH AN ANTI-TUMOUR ACTION | STERIX LTD (GB) | 2010-11-24 | — | — | EP | claimed |