Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382988 | 0.86 | HTR1A (0.41) | ALDH1A1KDM4ELMNABCHE | |
| SCHEMBL3381652 | 0.85 | CHRNA7 (0.33) | — | |
| SCHEMBL3382426 | 0.83 | CHRNA7 (0.32) | — | |
| SCHEMBL3382541 | 0.83 | CREBBP (0.42) | ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL3384341 | 0.78 | CHRNA7 (0.36) | ALDH1A1KMT2AHSP90AA1LMNA | |
| SCHEMBL3384638 | 0.77 | KDM4E (0.32) | GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL3383083 | 0.75 | SETD7 (0.35) | — | |
| SCHEMBL3384775 | 0.74 | BRD4 (0.37) | GAA | |
| Trifluoroacetic Acid SCHEMBL3382424 | 0.73 | KDM1A (0.36) | — | |
| SCHEMBL4669628 | 0.73 | SETD7 (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896467-B1 | TRICYCLIC OPIOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-01 | — | — | EP | claimed |