Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378260 | 0.85 | CD81 (0.39) | TSHRAKR1C3CHRM2CHRM4CHRM5 | |
| SCHEMBL3375934 | 0.83 | TSHR (0.36) | TSHRAKR1C3CHRM2CHRM4CHRM5 | |
| SCHEMBL3379259 | 0.77 | CYP2C9 (0.39) | AKR1C3ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL16293142 | 0.72 | TSHR (0.54) | TSHRALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL780495 | 0.72 | EPHX1 (0.40) | — | |
| SCHEMBL1561557 | 0.70 | MAOA (0.45) | TSHRALDH1A1GAAOPRM1OPRL1 | |
| SCHEMBL16986566 | 0.70 | TSHR (0.38) | TSHRAKR1C3ICMTALDH1A1MEN1 | |
| SCHEMBL16986564 | 0.70 | TSHR (0.38) | TSHRAKR1C3ICMTALDH1A1MEN1 | |
| SCHEMBL664472 | 0.69 | CD81 (0.33) | — | |
| SCHEMBL21937563 | 0.69 | MAOA (0.43) | TSHRCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361376-B2 | Process of making a three-dimensional object | CMET INC. (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20100104804-A1 | Three-Dimensional Object Having Smoothed Fabricated Edge Surface | CMET INC. (JP) | 2010-04-29 | — | — | US | disclosed |