Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3383160 | 0.92 | GPR84 (0.47) | GPR84FFAR1CES2FFAR4PLA2G2C | |
| Acetic Acid SCHEMBL28080807 | 0.90 | TSHR (0.45) | GPR84FFAR1CES2TSHRPLA2G2C | |
| Acetic Acid SCHEMBL3380365 | 0.90 | TSHR (0.45) | GPR84FFAR1CES2TSHRPLA2G2C | |
| SCHEMBL28593055 | 0.90 | TSHR (0.52) | GPR84FFAR1CES2TSHRMAPT | |
| SCHEMBL3380392 | 0.90 | TSHR (0.52) | GPR84FFAR1CES2TSHRMAPT | |
| Glycolic Acid SCHEMBL28379062 | 0.89 | GPR84 (0.46) | GPR84FFAR1CES2TSHRFFAR4 | |
| Acetic Acid SCHEMBL15793456 | 0.88 | GPR84 (0.58) | GPR84FFAR1FFAR4MAPTLCK | |
| Ether SCHEMBL3382911 | 0.86 | GPR84 (0.48) | GPR84FFAR1CES2FFAR4MAPT | |
| Acetic Acid SCHEMBL3379500 | 0.86 | GPR84 (0.52) | GPR84FFAR1FFAR4MAPTLCK | |
| Acetic Acid SCHEMBL27559434 | 0.86 | TSHR (0.48) | CES2TSHRPLA2G2CALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118325433-A | Single-component water-based paint and preparation method and application thereof | 江门市制漆厂有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118324553-A | Preparation method of concrete molding curing agent | 南京腾恒新材料有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118185359-A | Preparation and application of waterproof repair paint for roof | 广东美涂士建材股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116875089-B | Single-component pasty heat-insulating waterproof slurry and preparation method thereof | 佛山市涂无忧建材有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-118005314-A | Antibacterial material and application thereof in quartz stone plate | 广东欧文莱陶瓷有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117986949-A | Light low-density water-based damping coating and composite damping coating system thereof | 青岛爱尔家佳新材料股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117965063-A | Preparation method and application of high-stain-resistance formaldehyde-removal scrubbing-resistant luxury artistic coating | 广东美涂士建材股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117701089-B | Composite liquid granite coating with high heat insulation performance | 山东信泰节能科技股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117925019-A | Antibacterial environment-friendly emulsion paint | 上海科丽艾环保科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117701089-A | Composite liquid granite coating with high heat insulation performance | 山东信泰节能科技股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-111113193-A | Glass processing technology without paper folding and sheet separation | 东莞市晶博光电有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-111117440-A | Application of UV protective oil in solving warping of float glass | 东莞市晶博光电有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-111077757-A | Stereoscopic watch dial and manufacturing process thereof | 东莞市晶博光电有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-111057243-A | Organic silicon resin, polymer cement waterproof coating and preparation method thereof | 芜湖东方雨虹建筑材料有限公司 | 2020-04-24 | — | — | CN | claimed |
| CN-110760243-A | Preparation method of wood waterproof paint | 安徽阜南县向发工艺品有限公司 | 2020-02-07 | — | — | CN | claimed |
| CN-110760209-A | Coating for home surface decoration | 安徽阜南县向发工艺品有限公司 | 2020-02-07 | — | — | CN | claimed |
| CN-110643241-A | Efficient water-based silicone-acrylic resin antirust paint | 含山县人和铸造有限公司 | 2020-01-03 | — | — | CN | claimed |
| CN-106147536-A | A kind of steel ring wheel anticorrosive paint | 安徽江淮车轮有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-106083189-A | A kind of curing compound | 科之杰新材料集团有限公司 | 2016-11-09 | — | — | CN | claimed |
| CN-105694647-A | Heat-absorbing paint | 广西超星太阳能科技有限公司 | 2016-06-22 | — | — | CN | claimed |