Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.78 |
| ▸ | NPC1 | O15118 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | RAF1 | P04049 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19461395 | 0.90 | RAB9A (0.63) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL13234413 | 0.88 | RAB9A (1.00) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL13234442 | 0.86 | MAPT (0.71) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL1257102 | 0.84 | RAB9A (0.72) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL28485665 | 0.84 | RAB9A (0.75) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL1255104 | 0.81 | MAPK14 (0.78) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL2951112 | 0.80 | RAB9A (0.77) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL3196132 | 0.80 | MAPK14 (0.67) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL13235188 | 0.80 | MAPK14 (0.59) | RAB9ANPC1MAPTHTTPOLB | |
| SCHEMBL1016156 | 0.79 | RAB9A (0.68) | RAB9ANPC1MAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |