SCHEMBL3379620

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6157657	0.89	ALDH1A1 (0.51)	ALDH1A1CYP4F2CYP4A11NPC1RAB9A
	SCHEMBL10352780	0.85	CES1 (0.52)	ALDH1A1TSHRCES2CES1GAA
	SCHEMBL18640578	0.83	ALDH1A1 (0.53)	ALDH1A1NPC1TSHRGAAHTT
	SCHEMBL18640576	0.83	ALDH1A1 (0.53)	ALDH1A1NPC1TSHRGAAHTT
	SCHEMBL25222615	0.83	GAA (0.59)	ALDH1A1CES2CES1GAAHTT
	SCHEMBL18825664	0.83	GAA (0.59)	ALDH1A1CES2CES1GAAHTT
	SCHEMBL5634680	0.83	GAA (0.59)	ALDH1A1CES2CES1GAAHTT
	SCHEMBL4382929	0.83	GAA (0.59)	ALDH1A1CES2CES1GAAHTT
	SCHEMBL10353082	0.83	GAA (0.59)	ALDH1A1CES2CES1GAAHTT
	SCHEMBL4373141	0.83	GAA (0.59)	ALDH1A1CES2CES1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.