SCHEMBL338

SCHEMBL338

CCOC(=O)N1c2ccccc2C=CC1OCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 1.00
LMNA P02545 2/20 1.00
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
P2RX4 Q99571 6/20 0.42
BCHE P06276 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 2/20 0.41
TSHR P16473 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GAA P10253 1/20 0.41
P2RX1 P51575 3/20 0.38
P2RX3 P56373 3/20 0.38
P2RX7 Q99572 2/20 0.38
PTBP1 P26599 1/20 0.38
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL367474 1.00 SMN1; SMN2 (1.00) SMN1; SMN2LMNAMEN1KMT2AP2RX4
SCHEMBL29367804 1.00 SMN1; SMN2 (1.00) SMN1; SMN2LMNAMEN1KMT2AP2RX4
SCHEMBL23705539 1.00 SMN1; SMN2 (1.00) SMN1; SMN2LMNAMEN1KMT2AP2RX4
Carbimide SCHEMBL10800076 0.95 SMN1; SMN2 (0.90) SMN1; SMN2LMNAMEN1KMT2AP2RX4
1,2-Dichloroethane SCHEMBL28697158 0.95 SMN1; SMN2 (0.90) SMN1; SMN2LMNAMEN1KMT2AP2RX4
SCHEMBL8608444 0.93 SMN1; SMN2 (0.86) SMN1; SMN2LMNAMEN1KMT2AP2RX4
Dimethylformamide SCHEMBL7714545 0.92 SMN1; SMN2 (0.84) SMN1; SMN2LMNAMEN1KMT2AP2RX4
SCHEMBL8063974 0.91 SMN1; SMN2 (0.82) SMN1; SMN2LMNAMEN1KMT2AP2RX4
SCHEMBL8608446 0.91 SMN1; SMN2 (0.82) SMN1; SMN2LMNAMEN1KMT2AP2RX4
SCHEMBL9188247 0.90 SMN1; SMN2 (0.82) SMN1; SMN2LMNAMEN1KMT2AP2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17811 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036845-A Cathepsin B-sensitive fatty acid-doxorubicin prodrug, albumin nanoparticle thereof, and preparation method and application thereof 沈阳药科大学 2026-05-15 CN claimed
CN-122036842-A Cathepsin B-sensitive fatty acid-irinotecan prodrug and albumin nanoparticle thereof, and preparation method and application thereof 沈阳药科大学 2026-05-15 CN claimed
CN-122011088-A Cyclic peptide compound and preparation method and application thereof 甫康生物科技(上海)股份有限公司 2026-05-12 CN claimed
US-20260109730-A1 Process For The Preparation Of (3Beta,24S)-25,25,25-Trifluoro-3-Methyl-26,27-Dinorergost-5-ene-3,24-Diol IND CHIMICA SRL (IT) 2026-04-23 US claimed
EP-4720072-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-04-08 EP claimed
US-20260078133-A1 RAS INHIBITORS Revolution Medicines, Inc. 2026-03-19 US claimed
US-20260078124-A1 METHODS OF PREPARING ERGOLINE ANALOGS UNIV CALIFORNIA (US) 2026-03-19 US claimed
EP-4688790-A1 MACROCYCLIC RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-02-11 EP claimed
US-20260028353-A1 MACROCYCLIC RAS INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2026-01-29 US claimed
US-12486286-B2 Process and polymorphic forms of bictegravir and its pharmaceutically acceptable salts or co-crystals thereof LAURUS LABS LIMITED (IN) 2025-12-02 US claimed
EP-0070021-B1 PROCESS FOR THE PREPARATION OF CYCLIC HEXAPEPTIDE MERCK & CO. INC. (US) 1986-01-08 EP claimed
US-4560504-A Carboxyl anchored immobilized antibodies UOP INC. (US) 1985-12-24 US claimed
EP-0023854-B1 SOLUBLE POLYMERS POSSESSING ANTICOAGULATING PROPERTIES, PROCESS FOR PREPARING THEM AND THEIR USE AS DRUGS WITH ANTICOAGULATING ACTION Fougnot, Christine (FR) 1984-12-12 EP claimed
EP-0124068-A1 New derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same LEHNER A.G. (CH) 1984-11-07 EP claimed
US-4434228-A WITH POILYCARBOXYLIC ACID GENEX CORPORATION (US) 1984-02-28 US claimed
EP-0090100-A1 Insoluble polymers with anti-coagulating properties, articles containing them and methods of manufacture Fougnot, Christine (FR) 1983-10-05 EP claimed
EP-0070021-A1 Process for the preparation of cyclic hexapeptide MERCK & CO. INC. (US) 1983-01-19 EP claimed
EP-0061187-A1 Bicyclic lactams as antihypertensives MERCK & CO. INC. (US) 1982-09-29 EP claimed
EP-0023854-A1 Soluble polymers possessing anticoagulating properties, process for preparing them and their use as drugs with anticoagulating action Fougnot, Christine (FR) 1981-02-11 EP claimed
US-4238473-A LOWER CARBOHYDRATES HAVING A BRIDGING ARM GLYCOSIDICALLY LINKED TO AN ALDOSE MOIETY CHEMBIOMED LIMITED (CA) 1980-12-09 US claimed