Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375933 | 1.00 | PPARG (0.51) | PPARGPPARALMNAL3MBTL1KMT2A | |
| SCHEMBL1714102 | 1.00 | PPARG (0.51) | PPARGPPARALMNAL3MBTL1KMT2A | |
| SCHEMBL541965 | 1.00 | PPARG (0.51) | PPARGPPARALMNAL3MBTL1KMT2A | |
| SCHEMBL1714197 | 1.00 | PPARG (0.51) | PPARGPPARALMNAL3MBTL1KMT2A | |
| Water SCHEMBL3347709 | 0.98 | PPARG (0.50) | PPARGPPARALMNAL3MBTL1KMT2A | |
| Water SCHEMBL2789432 | 0.98 | PPARG (0.50) | PPARGPPARALMNAL3MBTL1KMT2A | |
| SCHEMBL27510640 | 0.90 | PPARG (0.45) | PPARGPPARALMNAL3MBTL1KMT2A | |
| SCHEMBL11708010 | 0.90 | PPARG (0.53) | PPARGPPARALMNAL3MBTL1KMT2A | |
| SCHEMBL1974348 | 0.88 | PPARG (0.54) | PPARGPPARALMNAL3MBTL1KMT2A | |
| SCHEMBL2952466 | 0.88 | PPARG (0.54) | PPARGPPARALMNAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230160-A1 | PROCESS FOR THE PREPARATION OF 4-((6BR,10AS)-3-METHYL-2,3,6B,9,10,10A-HEXAHYDRO-1H,7H-PYRIDO[3',4':4,5]PYRROLO[1,2,3-DE]QUINOXALIN-8-YL)-1-(4-FLUORO-PHENYL)-BUTAN-1-ONE AND INTERMEDIATES THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2025-07-17 | — | — | US | claimed |
| CN-118420658-B | Preparation method of chiral triazine compound | 天津辰欣药物研究有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118420658-A | Preparation method of chiral triazine compound | 天津辰欣药物研究有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-117964625-A | Preparation method of high-optical-purity ponatinib intermediate | 安徽万邦医药科技股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2023195027-A1 | PROCESS FOR THE PREPARATION OF 4-((6BR,10AS)-3-METHYL-2,3,6B,9,10,10A-HEXAHYDRO-1H,7H-PYRIDO[3',4':4,5]PYRROLO[1,2,3-DE]QUINOXALIN-8-YL)-1-(4-FLUORO-PHENYL)-BUTAN-1-ONE AND INTERMEDIATES THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2023-10-12 | — | — | WO | claimed |
| CN-116854642-A | Preparation method of (S) -2-piperazine acetonitrile and hydrochloride thereof | 重庆博腾制药科技股份有限公司 | 2023-10-10 | — | — | CN | claimed |
| WO-2022157633-A1 | ENANTIOMERICALLY PURE DESGLYMIDODRINE AND PROCESS FOR PREPARATION THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2022-07-28 | — | — | WO | claimed |
| CN-108289457-B | Process for preparing antifungal compounds | 迈科维亚医药公司 | 2021-08-06 | — | — | CN | claimed |
| CN-110935024-A | Long acting compositions | 合肥合源药业有限公司 | 2020-03-31 | — | — | CN | claimed |
| WO-2015063795-A2 | NOVEL PROCESS FOR PREPARATION OF OPTICALLY PURE NOREPHEDRINE AND ITS DERIVATIVES | LAURUS LABS PRIVATE LIMITED (IN) | 2015-05-07 | — | — | WO | claimed |
| EP-1587801-A1 | A PROCESS FOR PREPARING DULOXETINE AND INTERMEDIATES FOR USE THEREIN | Cipla Ltd. (IN) | 2005-10-26 | — | — | EP | claimed |
| WO-2004056795-A1 | A PROCESS FOR PREPARING DULOXETINE AND INTERMEDIATES FOR USE THEREIN | CIPLA LTD (IN) | 2004-07-08 | — | — | WO | claimed |
| EP-0787115-B1 | PROCESS FOR PRODUCING DERIVATIVES OF 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO[3a,3,2-ef][2]BENZAZEPINE | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2000-01-05 | — | — | EP | claimed |
| EP-0530335-B1 | DIPHOSPHONIC ACID DERIVATES AS INTERMEDIATES FOR THE PRODUCTION OF DIPHOSPHINE LIGANDS | HOFFMANN LA ROCHE (CH) | 1996-08-14 | — | — | EP | claimed |
| EP-0530336-B1 | CHIRAL PHOSPHINES | HOFFMANN LA ROCHE (CH) | 1996-03-06 | — | — | EP | claimed |
| EP-0575064-B1 | Process for the resolution of 3-dimethylamino-2-methylpropiophenone (3-damp) | MALLINCKRODT CHEMICAL INC (US) | 1995-10-25 | — | — | EP | claimed |
| US-5326782-A | Salts derived from 26-(dialkylaminoalkylsulphonyl)pristinamycin IIB | RHONE-POULENC RORER S.A. (FR) | 1994-07-05 | — | — | US | claimed |
| EP-0575064-A1 | Process for the resolution of 3-dimethylamino-2-methylpropiophenone (3-damp) | Mallinckrodt Chemical, Inc. (US) | 1993-12-22 | — | — | EP | claimed |
| US-5227526-A | Resolution of 3-dimethylamino-2-methylpropiophenone (3-DAMP) | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1993-07-13 | — | — | US | claimed |
| US-4072698-A | OPTICALLY ACTIVE ACIDS WITH KETONE OR ALDEHYDE CATALYST | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250230160-A1 | PROCESS FOR THE PREPARATION OF 4-((6BR,10AS)-3-METHYL-2,3,6B,9,10,10A-HEXAHYDRO-1H,7H-PYRIDO[3',4':4,5]PYRROLO[1,2,3-DE]QUINOXALIN-8-YL)-1-(4-FLUORO-PHENYL)-BUTAN-1-ONE AND INTERMEDIATES THEREOF | CYP1B1, CYP4B1, CYP7A1 | PPARG 4402/4885PPARA 4271/4885LMNA 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.