SCHEMBL375933

SCHEMBL375933

Cc1ccc(O[C@@H](C(=O)O)[C@@H](Oc2ccc(C)cc2)C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.51
PPARA Q07869 4/20 0.51
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
GAA P10253 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LDHA P00338 1/20 0.45
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
NLRP1 Q9C000 1/20 0.44
ACHE P22303 1/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338001 1.00 PPARG (0.51) PPARGPPARALMNAL3MBTL1KMT2A
SCHEMBL1714102 1.00 PPARG (0.51) PPARGPPARALMNAL3MBTL1KMT2A
SCHEMBL541965 1.00 PPARG (0.51) PPARGPPARALMNAL3MBTL1KMT2A
SCHEMBL1714197 1.00 PPARG (0.51) PPARGPPARALMNAL3MBTL1KMT2A
Water SCHEMBL3347709 0.98 PPARG (0.50) PPARGPPARALMNAL3MBTL1KMT2A
Water SCHEMBL2789432 0.98 PPARG (0.50) PPARGPPARALMNAL3MBTL1KMT2A
SCHEMBL27510640 0.90 PPARG (0.45) PPARGPPARALMNAL3MBTL1KMT2A
SCHEMBL11708010 0.90 PPARG (0.53) PPARGPPARALMNAL3MBTL1KMT2A
SCHEMBL1974348 0.88 PPARG (0.54) PPARGPPARALMNAL3MBTL1KMT2A
SCHEMBL2952466 0.88 PPARG (0.54) PPARGPPARALMNAL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024110862-A9 PROCESS FOR PREPARING ZANUBRUTINIB OLON S.P.A. (IT) 2024-11-28 WO claimed
WO-2024110862-A1 PROCESS FOR PREPARING ZANUBRUTINIB OLON S.P.A. (IT) 2024-05-30 WO claimed
EP-3336079-A1 (-)-(2R,3S)-2-AMINO-3-HYDROXY-3-PYRIDIN-4-YL-1-PYRROLIDIN-1-YL-PROPAN-1-ONE (L)-(+) TARTRATE SALT, ITS METHOD OF PRODUCTION AND USE ALLERGAN, INC. (US) 2018-06-20 EP claimed
EP-3033327-B1 (-)-(2R,3S)-2-AMINO-3-HYDROXY-3-PYRIDIN-4-YL-1-PYRROLIDIN-1-YL-PROPAN-1-ONE (L)-(+) TARTRATE SALT, ITS METHOD OF PRODUCTION AND USE ALLERGAN INC (US) 2018-01-03 EP claimed
EP-1884514-B1 METHOD FOR THE RESOLUTION OF 2-AMINO-6-PROPYLAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOL AND INTERMEDIATE COMPOUNDS CRYSTAL PHARMA SAU (ES) 2017-04-12 EP claimed
US-9242935-B2 (-)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, its method of production and use ALLERGAN, INC. (US) 2016-01-26 US claimed
EP-2155756-B1 PROCESSES FOR THE PREPARATION OF CLOPIDOGREL WOCKHARDT LTD (IN) 2015-08-05 EP claimed
US-9085509-B2 Process for preparing fesoterodine ALEMBIC PHARMACEUTICALS LIMITED (IN) 2015-07-21 US claimed
EP-2686288-B1 A PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LTD (IN) 2015-03-25 EP claimed
US-8952173-B2 Method for the resolution of 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazol and intermediate compounds CRYSTAL PHARMA, S.A.U. (ES) 2015-02-10 US claimed
US-6855820-B2 Pharmaceutically active morpholinol SMITHKLINE BEECHAM CORPORATION (US) 2005-02-15 US claimed
CN-1575282-A Lactam compound LILLY CO ELI (US) 2005-02-02 CN claimed
US-20040248878-A1 Lactam compound KOENIG THOMAS MITCHELL (US) 2004-12-09 US claimed
EP-1353910-A2 LACTAM COMPOUND ELI LILLY AND COMPANY (US) 2003-10-22 EP claimed
EP-1024137-B1 RESOLUTION OF AMINES ESTEVE LABOR DR (ES) 2003-09-24 EP claimed
US-20030027827-A1 Pharmaceutically active morpholinol SMITHKLINE BEECHAM CORPORATION 2003-02-06 US claimed
WO-2002040451-A2 LACTAM COMPOUND ELI LILLY AND COMPANY (US) 2002-05-23 WO claimed
US-6187930-B1 REACTING SELECTED AMINE WITH OPTICALLY ACTIVE ACID SELECTED FROM (+)-DITOLUYL-L-TARTARIC ACID AND/OR (-)-DITOLUYL-L-TARTARIC ACID IN SOLVENT TO FORM DIASTEROISOMERIC SALT, SEPARATING, ISOLATING ENANTIOMER LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2001-02-13 US claimed
EP-1024137-A1 RESOLUTION OF AMINES LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2000-08-02 EP claimed
US-4458084-A Cyclopentene derivatives THE UPJOHN COMPANY (US) 1984-07-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040248878-A1 Lactam compound AAAS, CHLSN, APH1B PPARG 3679/4885PPARA 3343/4885LMNA 919/4885
US-20030027827-A1 Pharmaceutically active morpholinol ACHE, COMT, MGLL PPARG 2515/4885PPARA 2398/4885LMNA 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.