Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381212 | 0.93 | CNR2 (0.53) | CNR2CYP3A4CYP2C9CYP1A2PTK2 | |
| SCHEMBL3378372 | 0.91 | CNR2 (0.53) | CNR2CYP3A4CYP2C9CYP1A2PTK2 | |
| SCHEMBL3382862 | 0.86 | CNR2 (0.59) | CNR2CYP3A4CYP2C9CYP1A2PTK2 | |
| SCHEMBL3379589 | 0.86 | CNR2 (0.52) | CNR2CYP3A4CYP2C9CYP1A2PTK2 | |
| SCHEMBL3381287 | 0.85 | CNR2 (0.49) | CNR2CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3382360 | 0.85 | CNR2 (0.50) | CNR2CYP3A4CYP2C9CYP1A2PTK2 | |
| SCHEMBL3377534 | 0.85 | CNR2 (0.66) | CNR2CYP3A4CYP2C9CYP1A2LRRK2 | |
| SCHEMBL3378926 | 0.84 | CNR2 (0.64) | CNR2CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3381292 | 0.84 | CNR2 (0.59) | CNR2CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL3379101 | 0.81 | CNR2 (0.76) | CNR2CYP3A4CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878725-B1 | Pyrimidine derivatives and their use as CB2 modulators | GLAXO GROUP LTD (GB) | 2010-11-24 | — | — | EP | claimed |