Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17429828 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL17429830 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL31718131 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL17429825 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL17429829 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL25022297 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL17429827 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL15489697 | 0.97 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL10945821 | 0.93 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 | |
| SCHEMBL87766 | 0.93 | TSHR (0.50) | TSHRTHRBLMNAHSD17B10CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9194319-A | — | — | None | — | — | JP | disclosed |
| WO-2019014491-A1 | METHODS FOR INHIBITION OF HAO1 (HYDROXYACID OXIDASE 1 (GLYCOLATE OXIDASE) GENE EXPRESSION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | disclosed |
| CN-106103665-A | Process for removing sulfur compounds from a hydrocarbon-containing stream | 巴斯夫欧洲公司 | 2016-11-09 | — | — | CN | disclosed |
| US-20100155303-A1 | METHOD FOR DESULFURIZATION OF HYDROCARBON OIL | JAPAN ENERGY CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-1923451-A1 | METHOD FOR DESULFURIZATION OF HYDROCARBON OIL | JAPAN ENERGY CORPORATION (JP) | 2008-05-21 | — | — | EP | disclosed |
| JP-H09194319-A | MOUSE REPELLENT AND ITS PRODUCTION | MATSUSHITA MANABU | 1997-07-29 | — | — | JP | disclosed |