Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17429827 | 1.00 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL15489697 | 1.00 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL17429828 | 1.00 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL17429829 | 1.00 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL17429825 | 1.00 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL25022297 | 1.00 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL31718131 | 1.00 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL3380195 | 0.97 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL867481 | 0.94 | TSHR (0.57) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL9330272 | 0.94 | TSHR (0.57) | TSHRTHRBHSD17B10CES2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11771715-B2 | Circular RNA compositions and methods | ORNA THERAPEUTICS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| EP-2961733-B1 | DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS | UNIV TUFTS (US) | 2021-01-13 | — | — | EP | disclosed |
| US-9765022-B2 | Disulfide compounds for delivery of pharmaceutical agents | TUFTS UNIVERSITY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160082126-A1 | NANOCOMPLEXES FOR DELIVERY OF SAPORIN | UNIV TUFTS (US) | 2016-03-24 | — | — | US | disclosed |
| US-20160009643-A1 | DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS | TRUSTEES OF TUFTS COLLEGE | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11771715-B2 | Circular RNA compositions and methods | RTCB, HNRNPA1, HNRNPAB | TSHR 1491/4885THRB 3160/4885HSD17B10 3622/4885 |
| US-20160009643-A1 | DISULFIDE COMPOUNDS FOR DELIVERY OF PHARMACEUTICAL AGENTS | P4HB, PDIA6, PDIA5 | TSHR 2132/4885THRB 3669/4885HSD17B10 990/4885 |
| US-20160082126-A1 | NANOCOMPLEXES FOR DELIVERY OF SAPORIN | SARNP, SAP30BP, SCP2 | TSHR 4368/4885THRB 4680/4885HSD17B10 824/4885 |
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | RTCB, HNRNPA1, HNRNPAB | TSHR 1491/4885THRB 3160/4885HSD17B10 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.