Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380564 | 1.00 | MAPT (0.47) | MAPTMEN1KMT2ATDP1THRB | |
| SCHEMBL864268 | 0.87 | MAPT (0.58) | MAPTTHRBHCAR3POLBALDH1A1 | |
| SCHEMBL864589 | 0.87 | MAPT (0.54) | MAPTMEN1KMT2ATDP1THRB | |
| SCHEMBL1838157 | 0.82 | MAPT (0.50) | MAPTMEN1KMT2ATDP1THRB | |
| SCHEMBL1838155 | 0.82 | MAPT (0.50) | MAPTMEN1KMT2ATDP1THRB | |
| SCHEMBL3379700 | 0.81 | KDM4E (0.41) | MAPTTHRBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL865328 | 0.79 | MAPT (0.47) | MAPTMEN1KMT2ATDP1THRB | |
| SCHEMBL865327 | 0.79 | MAPT (0.47) | MAPTMEN1KMT2ATDP1THRB | |
| SCHEMBL4172852 | 0.78 | TMEM97 (0.55) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL27615854 | 0.78 | MAPT (0.46) | MAPTHCAR3ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019208-A1 | FLAVIN DERIVATIVES | BIORELIX PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |