Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL864351 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL28423866 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL3380574 | 0.81 | MAPT (0.47) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL3380564 | 0.81 | MAPT (0.47) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL865777 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL3382378 | 0.78 | TAS2R14 (0.48) | KDM4EALDH1A1MAPTHDAC1FABP4 | |
| SCHEMBL864917 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL5563935 | 0.75 | TAS2R14 (0.40) | ALDH1A1HDAC2CA1CA2LMNA | |
| SCHEMBL4820499 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL4825292 | 0.72 | NQO2 (0.51) | KDM4EALDH1A1GAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019208-A1 | FLAVIN DERIVATIVES | BIORELIX PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |