Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 12/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380938 | 0.88 | KDR (0.46) | KDRFGFR3GABRA1GABRG2GABRB3 | |
| SCHEMBL3385891 | 0.86 | KDR (0.40) | KDRFGFR3 | |
| SCHEMBL3383023 | 0.86 | WNT3A (0.43) | KDRFGFR3 | |
| SCHEMBL3383562 | 0.85 | FGFR3 (0.39) | KDRFGFR3MEN1RAB9AKMT2A | |
| SCHEMBL3386499 | 0.83 | FGFR3 (0.38) | KDRFGFR3 | |
| SCHEMBL3196212 | 0.83 | KDR (0.46) | KDRFGFR3GABRA1GABRG2GABRB3 | |
| SCHEMBL3380739 | 0.82 | WNT3A (0.43) | KDRFGFR3 | |
| SCHEMBL3382431 | 0.81 | KDR (0.44) | KDRFGFR3 | |
| SCHEMBL3385390 | 0.81 | KDR (0.49) | KDRFGFR3GABRA1GABRG2GABRB3 | |
| SCHEMBL3379613 | 0.81 | KDR (0.37) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |