Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379297 | 0.78 | LMNA (0.39) | LMNAFDPSPGK1PGK2 | |
| SCHEMBL3981963 | 0.75 | LMNA (0.47) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL1191901 | 0.71 | LMNA (0.43) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL27620863 | 0.67 | — | — | |
| SCHEMBL13645503 | 0.67 | LMNA (0.39) | LMNAFDPS | |
| SCHEMBL335957 | 0.66 | — | — | |
| SCHEMBL3889334 | 0.65 | LMNA (0.50) | LMNAFDPSPGK1PGK2CA2 | |
| Phosphoric Acid SCHEMBL29620605 | 0.65 | LMNA (0.42) | LMNAFDPSPGK1PGK2CA2 | |
| SCHEMBL134918 | 0.63 | — | — | |
| SCHEMBL97568 | 0.63 | LMNA (0.56) | LMNAFDPSPGK1PGK2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |