Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 6/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377159 | 0.88 | HRH3 (0.41) | HRH3BCHEACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3377953 | 0.88 | HRH3 (0.39) | HRH3RORCS1PR5KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3377955 | 0.88 | HRH3 (0.39) | HRH3RORCS1PR5KDM4EALDH1A1 | |
| SCHEMBL3442329 | 0.86 | HRH3 (0.45) | HRH3BCHERORCACHES1PR5 | |
| SCHEMBL3442332 | 0.86 | HRH3 (0.45) | HRH3BCHERORCACHES1PR5 | |
| SCHEMBL3378184 | 0.85 | HRH3 (0.44) | HRH3BCHERORCS1PR5KDM4E | |
| SCHEMBL3380259 | 0.84 | HRH3 (0.45) | HRH3BCHEHRH1CCR3S1PR5 | |
| SCHEMBL3380460 | 0.83 | KCNH2 (0.45) | HRH3BCHEKDM4EKCNH2MCHR1 | |
| SCHEMBL3380037 | 0.82 | HRH3 (0.38) | HRH3BCHEHRH1CCR3KDM4E | |
| Hydrochloric Acid SCHEMBL3378531 | 0.82 | HRH3 (0.41) | HRH3RORCS1PR5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |