Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377536 | 0.90 | KMT2A (0.38) | HRH3BCHEMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL3378364 | 0.89 | HRH3 (0.41) | HRH3MEN1KMT2ACYP2A13KDM4E | |
| Hydrochloric Acid SCHEMBL3378366 | 0.89 | HRH3 (0.41) | HRH3MEN1KMT2ACYP2A13KDM4E | |
| SCHEMBL3378145 | 0.89 | KDM4E (0.45) | BCHEMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3380792 | 0.88 | HRH3 (0.39) | HRH3BCHEKDM4EALDH1A1ACHE | |
| Cyclopropane SCHEMBL3380221 | 0.86 | MEN1 (0.47) | HRH3BCHEMEN1KMT2AKDM4E | |
| Cyclohexane SCHEMBL3379321 | 0.86 | MEN1 (0.47) | HRH3BCHEMEN1KMT2AKDM4E | |
| SCHEMBL3379890 | 0.86 | MEN1 (0.47) | HRH3BCHEMEN1KMT2AKDM4E | |
| Cyclopentane SCHEMBL3378129 | 0.86 | MEN1 (0.47) | HRH3BCHEMEN1KMT2AKDM4E | |
| SCHEMBL3380259 | 0.86 | HRH3 (0.45) | HRH3BCHEMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |