Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568683 | 0.97 | KMT2A (0.38) | HRH3MEN1NPC1NFKB1RAB9A | |
| SCHEMBL2567151 | 0.89 | KMT2A (0.43) | MEN1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2567239 | 0.88 | KMT2A (0.42) | MEN1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2570785 | 0.87 | KMT2A (0.43) | MEN1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL3036059 | 0.85 | MEN1 (0.39) | HRH3MEN1NPC1NFKB1RAB9A | |
| SCHEMBL2565621 | 0.85 | KMT2A (0.44) | MEN1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL3028089 | 0.82 | KMT2A (0.40) | HRH3MEN1NPC1NFKB1RAB9A | |
| SCHEMBL2569473 | 0.82 | KMT2A (0.41) | MEN1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2569968 | 0.81 | RAB9A (0.39) | MEN1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL2571140 | 0.81 | KMT2A (0.41) | MEN1NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899330-B1 | SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT | BOEHRINGER INGELHEIM INT (DE) | 2010-11-24 | — | — | EP | disclosed |