Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378696 | 0.88 | SLC6A4 (0.49) | SLC6A4HTR6 | |
| SCHEMBL3377987 | 0.87 | SLC6A4 (0.46) | SLC6A4HTR6 | |
| SCHEMBL2280108 | 0.82 | SLC6A4 (0.69) | SLC6A4HTR6 | |
| SCHEMBL2284944 | 0.74 | SLC6A4 (0.74) | SLC6A4HTR6 | |
| SCHEMBL2288493 | 0.71 | SLC6A4 (0.70) | SLC6A4LMNAMAPT | |
| SCHEMBL3380976 | 0.71 | SLC6A4 (0.49) | SLC6A4HTR6 | |
| SCHEMBL2580468 | 0.69 | SLC6A4 (0.64) | SLC6A4HTR6 | |
| SCHEMBL14862428 | 0.69 | SLC6A4 (0.64) | SLC6A4HTR6 | |
| SCHEMBL2289191 | 0.68 | SLC6A4 (0.69) | SLC6A4 | |
| SCHEMBL3353389 | 0.68 | SLC6A4 (0.76) | SLC6A4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | claimed |