Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380982 | 0.88 | SLC6A4 (0.47) | SLC6A4HTR6 | |
| SCHEMBL3377987 | 0.81 | SLC6A4 (0.46) | SLC6A4HTR6 | |
| SCHEMBL2288493 | 0.81 | SLC6A4 (0.70) | SLC6A4NPC1RAB9A | |
| SCHEMBL8636638 | 0.72 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4970738 | 0.72 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2280108 | 0.71 | SLC6A4 (0.69) | SLC6A4HTR6 | |
| SCHEMBL2580468 | 0.71 | SLC6A4 (0.64) | SLC6A4HTR6 | |
| SCHEMBL14862428 | 0.71 | SLC6A4 (0.64) | SLC6A4HTR6 | |
| SCHEMBL20562112 | 0.70 | NPY1R (0.42) | — | |
| SCHEMBL27952400 | 0.70 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | claimed |