SCHEMBL338158

SCHEMBL338158

O=C(O)C1CC(C(=O)O)C(C(=O)O)C(C(=O)O)C1C(=O)O

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.48
POLB P06746 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
GABRR2 P28476 1/20 0.40
LMNA P02545 5/20 0.38
PMP22 Q01453 3/20 0.38
APEX1 P27695 2/20 0.38
KDM4E B2RXH2 2/20 0.38
TSHR P16473 2/20 0.38
GMNN O75496 1/20 0.38
TFPI2 P48307 1/20 0.38
TP53 P04637 1/20 0.38
NFKB1 P19838 1/20 0.38
THPO P40225 1/20 0.38
CYP2C19 P33261 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2C9 P11712 1/20 0.37
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9782984 1.00 GABRR1 (0.48) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL16062666 1.00 GABRR1 (0.48) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL9782988 1.00 GABRR1 (0.48) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL8628131 0.97 GABRR1 (0.50) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL22039 0.97 GABRR1 (0.50) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL2697233 0.97 GABRR1 (0.50) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL770971 0.97 GABRR1 (0.50) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL9782991 0.97 GABRR1 (0.50) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL13084744 0.97 GABRR1 (0.50) GABRR1POLBTDP1GABRR2LMNA
SCHEMBL503468 0.97 GABRR1 (0.50) GABRR1POLBTDP1GABRR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118743062-A Composition for forming electrode 日产化学株式会社 2024-10-01 CN disclosed
US-10881758-B2 Water-permeability-imparting agent, water-permeable fiber, non-woven fabric, and water-absorbing article SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-05 US disclosed
EP-2738222-B1 THERMOPLASTIC RESIN COMPOSITION FOR IMPACT ABSORBING MEMBER AND METHOD FOR PRODUCING SAME TORAY INDUSTRIES (JP) 2018-09-26 EP disclosed
US-20180000979-A1 WATER-PERMEABILITY-IMPARTING AGENT, WATER-PERMEABLE FIBER, NON-WOVEN FABRIC, AND WATER-ABSORBING ARTICLE SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2018-01-04 US disclosed
EP-2003158-B1 DENDRITIC POLYESTER, METHOD FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION TORAY INDUSTRIES (JP) 2017-07-05 EP disclosed
US-20170152347-A1 AMIDE DENDRIMER COMPOSITIONS GENZYME CORP (US) 2017-06-01 US disclosed
US-9334482-B2 Thermoplastic resin composition for impact absorbing member and method for producing same TORAY INDUSTRIES, INC. (JP) 2016-05-10 US disclosed
US-20150321996-A1 AMIDE DENDRIMER COMPOSITIONS GENZYME CORPORATION 2015-11-12 US disclosed
US-9066972-B2 Amide dendrimer compositions GENZYME CORPORATION (US) 2015-06-30 US disclosed
US-8900560-B2 Amide dendrimer compositions GENZYME CORPORATION (US) 2014-12-02 US disclosed
US-20100069500-A1 AMIDE DENDRIMER COMPOSITIONS GENZYME CORPORATION (US) 2010-03-18 US disclosed
US-20090118417-A1 Dendritic Polymer, Method for Producing the Same, and Thermoplastic Resin Composition TORAY INDUSTRIES, INC. (JP) 2009-05-07 US disclosed
EP-2003158-A9 DENDRITIC POLYESTER, METHOD FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2009-05-06 EP disclosed
EP-2003158-A2 DENDRITIC POLYESTER, METHOD FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2008-12-17 EP disclosed
US-4467100-A Epoxy resin compositions cured with imide-amine at ambient temperatures to afford products having useful properties at high temperatures LORD CORPORATION (US) 1984-08-21 US disclosed
US-4340715-A Epoxy resin compositions cured with imide-amines LORD CORPORATION (US) 1982-07-20 US disclosed
US-4207405-A ANTISCALING AND ANTIDEPOSIT AGENTS FOR WATER TREATMENT THE B. F. GOODRICH COMPANY (US) 1980-06-10 US disclosed
EP-0001561-A1 Water-soluble phosphorus containing carboxylic polymers The B.F. GOODRICH Company (US) 1979-05-02 EP disclosed
US-4128492-A Process of producing a cyclohexane-1,2,3,4-tetracarboxylic acid-containing scale inhibitor JOH. A. BENCKISER GMBH (DE) 1978-12-05 US disclosed
US-4043930-A PREVENTION OF SCALE FORMATION JOH. A. BENCKISER GMBH (DT) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069500-A1 AMIDE DENDRIMER COMPOSITIONS FABP2, PHOSPHO1, PAM GABRR1 2167/4885POLB 2395/4885TDP1 3877/4885
US-20150321996-A1 AMIDE DENDRIMER COMPOSITIONS FABP2, PHOSPHO1, PAM GABRR1 2167/4885POLB 2395/4885TDP1 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.