SCHEMBL3381683

SCHEMBL3381683

CCOc1ccc(-c2ccccc2Cl)cc1OC1CNC1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.54
HTR6 P50406 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12370779 0.86
SCHEMBL2280711 0.86
Hydrochloric Acid SCHEMBL2274917 0.85
SCHEMBL12370776 0.83
SCHEMBL2272529 0.75
SCHEMBL12370777 0.74
SCHEMBL2278124 0.74 SLC6A4 (0.53) SLC6A4HTR6
SCHEMBL27902945 0.73 ALDH1A1 (0.65)
SCHEMBL2280002 0.73 HTR2A (0.51) SLC6A4
Trifluoroacetic Acid SCHEMBL2277163 0.73 SUCNR1 (0.48) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010059390-A1 MODULATORS OF SEROTONIN RECEPTOR JANSSEN PHARMACEUTICA NV (BE) 2010-05-27 WO disclosed