SCHEMBL3381733

SCHEMBL3381733

C=C[Si](C)(C)c1ccc(OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 1/20 0.48
CA14 Q9ULX7 1/20 0.48
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
ALDH1A1 P00352 5/20 0.45
CYP3A4 P08684 4/20 0.45
TP53 P04637 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TSHR P16473 2/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
ACHE P22303 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2A6 P11509 1/20 0.40
KDM4E B2RXH2 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11748278 0.86 MAPT (0.53) CA1CA2ALDH1A1TP53SMN1; SMN2
SCHEMBL22041208 0.84 NR1H2 (0.48) NR1H2NR1H3ALDH1A1CYP3A4TP53
SCHEMBL678612 0.83 NR1H2 (0.59) NR1H2NR1H3
SCHEMBL31231936 0.79 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL2579803 0.77 NR1H2 (0.53) NR1H2NR1H3
SCHEMBL3378809 0.75 NR1H2 (0.52) CA1CA2CA7CA9NR1H2
SCHEMBL275936 0.75 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL19862402 0.74 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL28701305 0.74 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL275937 0.74 CA1 (0.61) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909356-A Medical polyurethane material and preparation method thereof 温州大学新材料与产业技术研究院 2020-11-10 CN claimed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
CN-118930574-A Electrophilic cross coupling method for aryl fluorosulfonate and vinyl chlorosilane 南京工业大学 2024-11-12 CN disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 US disclosed
CN-111909356-A Medical polyurethane material and preparation method thereof 温州大学新材料与产业技术研究院 2020-11-10 CN disclosed
CN-111909356-A Medical polyurethane material and preparation method thereof 温州大学新材料与产业技术研究院 2020-11-10 CN disclosed
EP-3691894-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM Maxterial, Inc. (US) 2020-08-12 EP disclosed
WO-2020116367-A1 POLYBUTADIENE AND METHOD FOR PRODUCING SAME 宇部興産株式会社 2020-06-11 WO disclosed
US-20190186035-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2019-06-20 US disclosed
WO-2019067950-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL, INC. (US) 2019-04-04 WO disclosed
US-20180028029-A1 DRYING APPARATUS COMPRISING A HYDROPHOBIC MATERIAL HAGHDOOST ATIEH (US) 2018-02-01 US disclosed
US-20170334170-A1 ARTICLES INCLUDING ADHESION ENHANCING COATINGS AND METHODS OF PRODUCING THEM HAGHDOOST ATIEH (US) 2017-11-23 US disclosed
US-20170190139-A1 COATINGS AND COATED SURFACES WITH SELECTED SURFACE CHARACTERISTICS AND FEATURES HAGHDOOST ATIEH (US) 2017-07-06 US disclosed
EP-1452549-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO LTD (JP) 2010-11-17 EP disclosed
US-7629419-B2 Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO., LTD. (JP) 2009-12-08 US disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed