Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678612 | 0.92 | NR1H2 (0.59) | NR1H2NR1H3 | |
| SCHEMBL12032183 | 0.89 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL12032181 | 0.85 | NR1H2 (0.43) | NR1H2NR1H3 | |
| SCHEMBL3378809 | 0.82 | NR1H2 (0.52) | NR1H2NR1H3 | |
| SCHEMBL10540578 | 0.80 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL31231940 | 0.80 | NR1H2 (0.55) | NR1H2NR1H3 | |
| SCHEMBL2558126 | 0.80 | NR1H2 (0.55) | NR1H2NR1H3 | |
| SCHEMBL10324259 | 0.80 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL3378627 | 0.80 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL7712417 | 0.80 | ALDH1A1 (0.52) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048977-B2 | Organosilicon polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-01 | — | — | US | claimed |
| US-20090069525-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-03-12 | — | — | US | claimed |
| WO-2007130014-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-15 | — | — | WO | claimed |
| US-8335148-B2 | Polymerizable compound, polymerizable composition, optical material, optical element and optical head device | ASAHI GLASS COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-8048977-B2 | Organosilicon polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-01 | — | — | US | disclosed |
| EP-1561449-B1 | Addition cross-linking two-component silicon material containing rigid and/or bulky groups annd having a high flexural strength and E-modul | KETTENBACH GMBH & CO KG (DE) | 2009-08-05 | — | — | EP | disclosed |
| US-20090069525-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-03-12 | — | — | US | disclosed |
| WO-2007130014-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-15 | — | — | WO | disclosed |
| EP-1561449-A1 | Addition cross-linking two-component silicon material containing rigid and/or bulky groups annd having a high flexural strength and E-modul | Kettenbach GmbH & CO. KG (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050171233-A1 | Two-component dental material crosslinking by addition, by way of a hydrosilylation reaction, having rigid and/or voluminous groups as well as great flexural strength | KETTENBACH GMBH & CO. KG | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110310721-A1 | POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, OPTICAL ELEMENT AND OPTICAL HEAD DEVICE | H1-0, H1-2, SUV39H2 | NR1H2 440/4885NR1H3 401/4885 |
| US-20050171233-A1 | Two-component dental material crosslinking by addition, by way of a hydrosilylation reaction, having rigid and/or voluminous groups as well as great flexural strength | VCL, ALG3, ORMDL3 | NR1H2 2630/4885NR1H3 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.