Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15176842 | 0.73 | CYP4F2 (0.39) | CD274 | |
| SCHEMBL29522156 | 0.72 | CYP4F2 (0.35) | CD274 | |
| SCHEMBL137046 | 0.72 | CYP4F2 (0.35) | CD274 | |
| SCHEMBL30365739 | 0.71 | MTOR (0.49) | CD274 | |
| SCHEMBL150074 | 0.71 | MTOR (0.57) | — | |
| SCHEMBL482091 | 0.69 | CYP4F2 (0.34) | CD274 | |
| SCHEMBL2144561 | 0.66 | ALDH1A1 (0.36) | CD274 | |
| SCHEMBL153542 | 0.63 | CYP2C19 (0.35) | CD274 | |
| SCHEMBL2145172 | 0.62 | CYP1A2 (0.40) | CD274 | |
| SCHEMBL482277 | 0.61 | CYP4F2 (0.36) | CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117213-B | Heteroaryl compounds and methods for their synthesis and purification | 西格诺药品有限公司 | 2022-03-18 | — | — | CN | disclosed |
| WO-2010062571-A1 | MTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE MTOR/P13K/AKT PATHWAY | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-06-03 | — | — | WO | disclosed |