Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 10/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 4/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379975 | 0.84 | GRIK1 (0.47) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL11712204 | 0.77 | GSR (0.58) | GRIK1GRIK2GRM1GRM2GGT1 | |
| SCHEMBL7906647 | 0.76 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL197013 | 0.76 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL3382098 | 0.76 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL9545322 | 0.76 | SLC7A5 (0.68) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL29024969 | 0.76 | SLC7A5 (0.68) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL600881 | 0.76 | SLC7A5 (0.68) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| Hydrochloric Acid SCHEMBL8892666 | 0.73 | SLC7A5 (0.65) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL13057623 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |