SCHEMBL197013

SCHEMBL197013

CN(C)C(=O)CC(N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GRIK1 P39086 9/20 0.54
▸ SLC7A5 Q01650 1/20 0.50
▸ GRIK2 Q13002 5/20 0.48
▸ GRM1 Q13255 1/20 0.46
▸ GRM2 Q14416 1/20 0.46
▸ GRIA4 P48058 3/20 0.45
▸ GRIK3 Q13003 3/20 0.45
▸ GRIK5 Q16478 3/20 0.45
▸ SLC1A3 P43003 4/20 0.45
▸ SLC1A2 P43004 4/20 0.45
▸ SLC1A1 P43005 3/20 0.45
▸ GRIA2 P42262 2/20 0.44
▸ GRIA1 P42261 1/20 0.44
▸ PTGS1 P23219 1/20 0.42
▸ SLC7A11 Q9UPY5 1/20 0.42
▸ GGT1 P19440 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906647 1.00 GRIK1 (0.54) GRIK1SLC7A5GRIK2GRM1GRM2
Trifluoroacetic Acid SCHEMBL30191327 0.88 GRIK1 (0.44) GRIK1SLC7A5GRIK2GRM1GRM2
SCHEMBL13913802 0.81 DPP9 (0.39) GRIK1SLC7A5GRIK2
SCHEMBL13913742 0.81 DPP9 (0.39) GRIK1SLC7A5GRIK2
SCHEMBL1768449 0.77 GSR (0.58) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL197385 0.77 GSR (0.58) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL3096327 0.77 ALDH1A1 (0.39) GRIK1
SCHEMBL1768719 0.77 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
SCHEMBL1768717 0.77 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL16027034 0.77 GRIK1 (0.42) GRIK1SLC7A5GRIK2GRM1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56034608-A — — None — — JP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 — — EP disclosed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 — — EP disclosed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 — — US disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 — — WO disclosed
EP-4594336-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PeptiDream Inc. (JP) 2025-08-06 — — EP disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 — — WO disclosed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 — — WO disclosed
WO-2024073605-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC. (JP) 2024-04-04 — — WO disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 — — US disclosed
US-6194143-B1 MEASUREMENT ACTIVITY BY MONITORING SUBSTRATE CLEAVAGE BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 2001-02-27 — — US disclosed
US-6057287-A KUNITZ DOMAIN HAVING DISULFIDE BONDS AT CYSTINE 5-55, 14-38, 30-51 POSITIONS DYAX CORP. (US) 2000-05-02 — — US disclosed
EP-0948640-A2 IMPROVED SUBSTRATES FOR HUMAN CYTOMEGALOVIRUS PROTEASE BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1999-10-13 — — EP disclosed
WO-1998029562-A2 IMPROVED SUBSTRATES FOR HUMAN CYTOMEGALOVIRUS PROTEASE BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1998-07-09 — — WO disclosed
EP-0388109-B1 Potato Production KOREA INST SCI & TECH (KR) 1995-03-15 — — EP disclosed
EP-0388109-A1 Potato Production KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1990-09-19 — — EP disclosed
US-4749716-A FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-07 — — US disclosed
US-4554007-A Geometrical isomer of 1-substituted-1-triazolylstyrenes, and their production and use as fungicide, herbicide and/or plant growth regulant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-19 — — US disclosed
JP-S5634608-A PREPARATION FOR CONTROLLING LAWN PYTHIUM PATCH BIHOU SHOKAI:KK 1981-04-06 — — JP disclosed
US-4244731-A APPLYING A CARBOXY DERIVATIVE OF A 2,6-DIMETHYLPHENOXY COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 GRIK1 1342/4885SLC7A5 3300/4885GRIK2 1549/4885
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP GRIK1 2914/4885SLC7A5 75/4885GRIK2 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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